Understanding Sleep Disorders with Autism

Following the 2017 identification of Nlgn3R451C (neuralin) mutation in patients with autism, animal sleep research has shown the gene alters brain activity and suggests a role in sleep/wake regulation in humans. (Biomed Central) This study piggybacks a 2013 study showing that the neuralin family of brain cells played a role in sleep and wakefulness in lab mice. (Research Gate) Thus, studies indicate some people on the spectrum may carry mutations that make them more prone to sleep problems. (APM).

Also, the most recent study demonstrated that melatonin, previously thought to help those with autism, is not beneficial.

Continued studies are recommended on the sleep disorders for those with Asd as up to 80% of those with autism are affected by insufficient sleep. (Biomed Central)

It has been suggested that the focus of study for autism and sleep has been slow in coming as research has focused on a cure for the condition, and on the social and behavioral aspects of the condition.