Hematologist (Pediatric) Questions Hematologist

I have some abnormal lymphocytes: should we worry?

My son is 15 and had just received his results from a hemogram. Since he was not eating properly and not gaining weight, his doctor made him pass a hemogram. Following the results, she wants to see him in January and says that we shouldn't worry. He has no other symptoms other than having time to time an headache. He's not tired. His Ferritine is normal. He received vaccination for HPV three weeks prior to his blood test.

His total white count blood is 4.3.
Neutrophils (ratio) : 0.343
Neutrophils (1.5)
Lymphocytes (ratio) : 0.481
Lymphocytes (2.0)
Monocytes (ratio) : 0.109

They also noticed some abnormal lymphocytes. Considering those results, what will or should be the next step taken by his doctor.

Male | 15 years old

4 Answers

No, you should not be worry. Follow your Dr. appointment.
The values may represent a normal occurrence that maybe a very mild infectious process could be in progress. However, at this point there is no concern. Now, check and maintain a log of the headaches. If the headaches are persistent take him to his healthcare provider for proper investigation.
The normal values are below.
WBC = white blood cells: most of the time indicates that you are fighting infection or inflammation. Normal range is 4,500 to 11,000 WBCs per microliter (4.5 to 11.0 x 109/L). There are three major classifications of WBCs. The main purpose oof WBCs, are to recognize intruders:
•Monocytes – They have the longer lifespan than other WBCs. They help to break down bacteria.
•Lymphocytes – They create antibodies to fight against bacteria, viruses, and other invaders to the body.
.Granulocytes – They kill and digest bacteria, fungi, and many other things. . .Neutrophils, Eosinophils and Basophils are a subset of granulocytes. .Basophils are mainly responsible for allergens. Eosinophils are responsible for parasitic infections.

RBC = Red blood cells Count: Measures how many red bloods cell count you have in the body. A red blood cell counts higher than 6.1 million RBCs in male and 5.4 million for females, and 5.5 million for children. High RBCs count can be due to multiple etiologies. They are dehydration, heart disease, Polycythemia vera, Bone marrow diseases that causes other etiologies in many other cells that are produced in the bone marrow. Low RBC indicates B12, Folate and B6 deficiency. Also could mean that you are bleeding internally.
HCT= Hematocrit is the percentage by volume of red blood cells, white blood cells, and platelets suspended in plasma.
MCV = Mean corpuscular volume = measures the average size and volume of red blood cell.
MCHC = Mean corpuscular hemoglobin concentration is a measurement of hemoglobin in a single red blood cell related to the volume of the cell.
RDW = Red Cell Distribution Width = test the different in volume and size of your RBC.
Platelets = (Thrombocytes), they stop bleeding by clumping and forming plugs.
Neutrophils = A type of white blood cell (Leukocytes) that are your first immune response. Thank you.
Sounds essentially normal. Not to worry.
Not specific often seen in viral infection. I would re-evaluate in a month. No reason to be concern.
I agree with your doctor, next step is follow up. In teenagers most common cause of abnormal lymphocytes is reactive (meaning body is reacting to some inflammation or infection). Sometimes these lymphocytes may persist for sometime. It should be followed up and further investigated if there are additional symptoms like sudden unintentional weight loss, night sweats or enlarged palpable lymph nodes. Overall, in your son's case, statistically, you don't need to worry.