RB Thomas, MD
Serum, to put it simply, is the fluid of the blood minus the red blood cells. Under well controlled circumstances, whole blood glucose is usually higher than serum glucose about 5 to 10 %.
As I stated, under well controlled circumstances, means that the home blood glucose testing meter must be well calibrated with two points glucose standards and the readings of those standards must be within the mean and standard deviation of the stated values.
The clinical laboratory, on the other hand,always perform calibration and runs quality control materials on a regular basis as mandated by the accrediting agents.
In general, home blood glucose testing is simply "Glucose Monitoring", which provide a close enough picture of the patient's diabetes status.
I hope this provides a simple answer to your question.