“Wellbutrin reset tolerance?”

Only taking Wellbutrin XL for 4 months shouldn’t be enough time for your body to no longer receive effect from it, but if you’re wanting to slowly ween off of it and then restart I would recommend trying to take one table every other day for 2 weeks, then every 2 days for 2 weeks, and then every 3 days for 2 weeks. After that you should be able stop it completely for a couple weeks and then begin taking it again daily. I would definitely advise a discussion with your physician about doing this though, and see if he wouldn’t want to just increase your dose of the medication. It can be safely taken up to 450mg per day, however it lowers the seizure threshold, especially when alcohol is consumed. I’m not suggesting that you drink or not, but being 21 years old and being in college I just wanted to make sure you were aware of the risks of taking Wellbutrin and drinking.

The answer is that's not how it works. I would not recommend abruptly stopping your medication like that. I do recommend discussing this issue with your prescriber. There are different categories of drugs that do what Wellbutrin does, so your prescriber has options to work with.

I would contact your prescriber for an alternative medication!

You don't want to abruptly stop your Wellbutrin, if you are stopping it you need to slowly wean off of it and then stay off of it for at least 4 weeks. However, you are not on the maximum dose and could ask your Doctor to increase it to 450mg daily to see if that helps you. 4 months is not very long to have been on the medication and see no effect due to tolerance, so I think a dose increase is probably the best thing to try here.

I would suggest talking with your doctor. He or she may increase the dose or frequency of your Wellbutrin to get desired effects