Neurologist Questions Multiple Sclerosis

Why does multiple sclerosis cause fatigue?

As far as I know, the disease just interferes with nerve signals between someone's brain and their extremities. But why does multiple sclerosis cause fatigue?

1 Answer

All of the autoimmune diseases cause fatigue. The immune system takes massive amounts of energy to function. Think about when you have had a cold or the flu. One of the most prominent symptoms is usually exhaustion. It’s hard to even get out of bed, right? With an autoimmune disease like MS, the body thinks that the immune system has to constantly be fighting off an infection, so uses a lot of energy all the time. Interestingly, when an MS patient tries a new, stronger med,the immediate effect they get is an increase in energy because the med has calmed the autoimmune activity.