Thrombocytosis is difficult to diagnose with physical check-up only.
During physical examination enlarged spleen can be detected along with other signs. Those signs may be similar with other blood diseases.
Therefore, some additional tests will be really important in confirming diagnosis like the following:
A routine blood test which will determine count of all blood cells and pathological cells and inclusions. A blood smear to see the characteristics of platelets like the size and activity. The doctor would to repeat the test because many other conditions may temporarily increase the amount of platelets.
If the blood count shows the number of thrombocytes more than 450,000 (normal range is 150,000-450,000), then the doctor is likely to look for an underlying cause.
bone marrow aspiration for further laboratory testing.
Since thrombocytosis is mostly associated to an underlying disease, therefore treating that disorder would be the priority.
In the case of reactive thrombocytosis, it is highly unlikely, that any kind of medications are needed to lower the platelet count.
Treating the main disease that led to thrombocytosis would lower the platelet count and prevent any complications.
But in the case of primary thrombocytosis which can lead to life-threatening condition, it should be treated by special methods namely, bone marrow transplantation or giving medications like fibrinolytics chronically according to schedule.
The following may help to prevent the development of thrombocytopenia and its complications:
avoid infections by following proper hygienic methods,
doing proper exercise and not exceeding required limits,
7 Risks and Complications
A family history of thrombocytosis or other blood conditions causing thrombocytosis can be a major risk factor.
Some additional risk factors include:
having kidney diseases,
splenectomy (removal of spleen),
having autoimmune disorders.
The major complication of increased amount of thrombocytes is thrombosis (clot formation) which may narrow or completely obliterate the lumen of the blood vessels leading to decreased or absence of blood flow to the organ associated to blood vessel which in turn results in organ failure.
This thrombus (clot) breaks out from the original place and lodging into a different place forming a clot into small vessels or capillaries, this is known as embolism.
This embolus (newly formed clot) may completely block the vessel resulting in organ failure.
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