1 What is Avc?

Brand: Avc

Generic: Sulfonamide (Vaginal Route)

Vaginal sulfonamides are used to treat certain vaginal infections. It works by inhibiting the growth and reproduction of bacteria. This product is available in cream and suppository.

2 What to Know Before Using

Tell to your doctor if you are allergic to Avc or to any other medications. You should also inform your healthcare providers if you are allergic to foods, dyes, or animals. Studies of this medication have only been tested for adults. Studies for pregnancy have not been tested for humans. Tell your doctor if you are pregnant or if you are planning to become pregnant while using this medication.

Breastfeeding while under Avc treatment can cause harmful infant effects since this drug can pass through breast milk. Stop breastfeeding while using this medicine. Vaginal sulfonamides may cause liver problems in nursing babies. These medications may also cause anemia in nursing babies with glucose-6-phosphate dehydrogenase deficiency.

Taking this medicine with any of the following medicines is not recommended and you may not be required to receive this medication. Otherwise, alternative medicine may be prescribed for your other medications.

  • Dofetilide
  • Levomethadyl
  • Methenamine

Taking this medicine with any of the following medicines is usually not recommended, but with exception in some cases. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.

  • Acecainide
  • Acenocoumarol
  • Ajmaline
  • Amiodarone
  • Amisulpride
  • Amitriptyline
  • Amoxapine
  • Amphetamine
  • Aprindine
  • Arsenic Trioxide
  • Astemizole
  • Azathioprine
  • Azimilide
  • Bretylium
  • Ceritinib
  • Chloral Hydrate
  • Chloroquine
  • Chlorpromazine
  • Clarithromycin
  • Dabrafenib
  • Dasabuvir
  • Desipramine
  • Dibenzepin
  • Digitalis
  • Disopyramide
  • Dolasetron
  • Doxepin
  • Droperidol
  • Enflurane
  • Erythromycin
  • Flecainide
  • Fluconazole
  • Fluoxetine
  • Foscarnet
  • Gemifloxacin
  • Halofantrine
  • Haloperidol
  • Halothane
  • Hydroquinidine
  • Ibutilide
  • Imipramine
  • Isoflurane
  • Isradipine
  • Leucovorin
  • Levomethadyl
  • Lidoflazine
  • Lorcainide
  • Mefloquine
  • Memantine
  • Mercaptopurine
  • Metformin
  • Methotrexate
  • Nortriptyline
  • Octreotide
  • Orlistat
  • Pentamidine
  • Pirmenol
  • Prajmaline
  • Probucol
  • Procainamide
  • Prochlorperazine
  • Propafenone
  • Proscillaridin
  • Pyrimethamine
  • Quinidine
  • Riluzole
  • Risperidone
  • Sematilide
  • Sertindole
  • Sotalol
  • Spiramycin
  • Sultopride
  • Tedisamil
  • Telithromycin
  • Topotecan
  • Trifluoperazine
  • Trimipramine
  • Vasopressin
  • Warfarin
  • Zotepine

Some medical conditions can interact with this medication. Tell your doctor if you have any of the following conditions:

  • Glucose-6-phosphate dehydrogenase deficiency
  • Kidney disease
  • Porphyria

3 Proper Usage

Use Avc exactly as prescribed by your doctor. To administer this medication, insert the applicator full with medication into the vagina. Do not stop this medication without the advice of your doctor or if your menstrual period starts during the time of treatment.
For sulfanilamide

  • For vaginal cream - one applicatorful (approximately 6 grams) inserted into the vagina once or twice a day for 30 days.
  • For vaginal suppositories - one suppository inserted into the vagina once or twice a day for 30 days.

For triple sulfa

  • For vaginal cream – initial dose is one applicatorful (approximately 4 to 5 grams) inserted into the vagina twice a day for 4 to 6 days. Afterwards, your doctor may lower your dose to one-half to one-quarter applicatorful twice a day. Use this medicine when you wake up and just before you go to bed.
  • For vaginal tablets - one tablet inserted into the vagina twice a day for 10 days.

If you miss a dose of this medicine, use it as soon as possible. However, if it is near for your next dose, skip the missed dose and start again to your regular dosing schedule. Do not take a double dose to make up for a missed one. Store the medication in a closed container at room temperature, away from heat, moisture, and direct light. Keep out of reach of children. Do not keep expired medications.

4 Precautions to Take

Check with your doctor if your symptoms did not improve within a few days, or if they become worse. You may wear a sanitary napkin or minipads to keep the medicine from staining your clothing. Do not use tampons while under Avc treatment since they may soak up too much of the medicine. Wear cotton panties and freshly washed underclothes.

Your partner is suggested to wear a condom during intercourse to prevent the infection from recurring. Do not stop using this medicine if you are sexually active. In addition, it may be required for your partner to be treated at the same time you are being treated to avoid passing the infection back and forth.

With regard to vaginal douching, some doctors recommend it before inserting the next dose of the medicine and some doctors don’t. If you do use a douche, it is not recommended to overfill the vagina with douche solution because this may force the solution up into the uterus and may cause inflammation and infection. You should not also douche if you are pregnant because it may cause risk to the baby.

5 Potential Side Effects

If any of the following side effects occur, check with your doctor right away:

  • Itching, burning, skin rash, redness, swelling, or other sign of irritation not present before use of this medicine
  • Burning at site of application

Less serious side effects:

  • Rash or irritation of penis of sexual partner

Not all side effects are listed above. If you notice any other effects, check with your healthcare professional.