Duloxetine, a selective serotonin and norepinephrine reuptake inhibitor (SSNRI), is indicated for patients with anxiety and depression.
It has also been found to be effective in treating pain secondary to diabetic peripheral neuropathy. It is indicated for people with fibromyalgia and chronic muscle and bone pain as well.
It is believed that its therapeutic effects, which again are pain relief and anti-depression, are brought about by the increased serotonergic and noradrenergic activity.
You can only purchase duloxetine with a physician’s order. It comes in a regular capsule or a delayed-release capsule.
2 What to Know Before Using
Discuss the pros and cons involved in using this medication before starting treatment. Usually, there are several factors you need to consider.
Oral duloxetine should not be given to patients who have had allergic reactions to similar medications. You must inform your doctor if you have had such reactions.
You also need to tell him or her about food, animal, dye, and other drug allergies. Studies on children aging 7 years and older have found that there aren’t age-related factors that could influence its effects.
However, studies on those younger than 7 years old have not been conducted. For geriatric patients, duloxetine must be used with caution because this age group is more sensitive to its effects.
They are also prone to falls. Not enough research has been done regarding the effects of duloxetine on pregnant women. The same goes for nursing mothers.
So duloxetine needs to be used with caution in these populations. The benefits must clearly outweigh the risks. c also interacts with other medications.
You should not use it if you are also taking isocarboxazid, linezolid, methylene blue, metoclopramide, procarbazine, phenelzine, rasagiline, safinamide, selegiline, thioridazine, and tranylcypromine.
Dose and frequency adjustment may be necessary when concomitantly taking acenocoumarol, phenprocoumon, and warfarin.
Concomitant use of the following medications is not normally recommended but can be necessary:
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