Azelastine and Fluticasone combination is an antihistamine and corticosteroid nasal spray that used to help treat symptoms of seasonal allergic rhinitis.
The mechanism of action of Azelastine is preventing the effects of histamine in the body which causes itching, sneezing, runny nose, and watery eyes, whereas, the fluticasone acts by preventing the inflammation that occurs with allergic reactions.
2 What to Know Before Using
Tell to your doctor if you are allergic to Azelastine and Fluticasone nasal spray or to any other medications.
You should also inform your healthcare providers if you are allergic to foods, dyes, or animals.
Studies have shown that the use of Azelastine and Fluticasone nasal spray has not demonstrated problems in children 12 years and older. Safety and effectiveness have not been established in children younger than 6 years.
Although this medicine have not demonstrated geriatric-specific problems, older patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients who are receiving Azelastine and fluticasone nasal spray.
Pregnancy C - The use of Azelastine and Fluticasone nasal spray during pregnancy is warranted only if benefits justify risks to the fetus and only when no alternative management is appropriate.
There are no adequate studies whether Azelastine and Fluticasone nasal spray can pass through breast milk or if it could cause harmful effects to the infant.
Discuss with your doctor if you are breastfeeding a baby.
Taking this medicine with any of the following medicines is usually not recommended, but with exception in some cases. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.
Aprepitant
Atazanavir
Boceprevir
Bupropion
Ceritinib
Clarithromycin
Cobicistat
Conivaptan
Dabrafenib
Darunavir
Dasabuvir
Donepezil
Fosaprepitant
Idelalisib
Imatinib
Indinavir
Itraconazole
Ketoconazole
Lumacaftor
Nefazodone
Nelfinavir
Nilotinib
Piperaquine
Pixantrone
Posaconazole
Ritonavir
Saquinavir
Telaprevir
Telithromycin
Tipranavir
Voriconazole
Taking Azelastine and Fluticasone nasal spray with Cimetidine may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.
Some medical conditions can interact with this medication.
Tell your doctor if you have any of the following conditions:
Use this medicine exactly as prescribed by your doctor.
Excessive use of this medication will increase the chance for side effects.
This medicine is only intended for use in the nose. Avoid contact in your eyes and mouth. If this medicine accidently gets in these areas, rinse these areas thoroughly and check with your doctor immediately.
Direction to use Azelastine and Fluticasone nasal spray:
Prime the spray when it is your first time to use it by pressing down fully the top of the pump 6 times or until a fine spray comes out. Prime it if it has not been used for 14 or more days.
Blow your nose softly before using the spray. Slightly tilt your head back and insert the tip of the nose piece into your nostril.
Close the opposite nostril by pinching it with a finger. Release 1 spray and at the same time, breathe in gently through the nostril.
Hold your breath for a few seconds then breathe out slowly through your mouth.
Spray the opposite nostril using the same steps.
After using the spray, do not blow your nose or tip your head back.
Wipe the tip of the outside of the nose piece with a clean, dry tissue or cloth and put the cap back on.
Discard the medicine after you consumed 120 sprays.
Recommended dosage for treatment of seasonal allergic rhinitis:
Adults and children 6 years of age and older—1 spray in each nostril twice a day. Each spray contains 137 micrograms of Azelastine and 50 mcg of Fluticasone.
Children younger than 6 years of age—Use and dose must be determined by your doctor.
If you miss a dose of this medicine, use it as soon as possible. However, if it is near for your next dose, skip the missed dose and start again to your regular dosing schedule. Do not take a double dose to make up for a missed one.
Store the medication in a closed container at room temperature, away from heat, moisture, and direct light. Keep out of reach of children. Do not keep expired medications.
4 Precautions to Take
Your doctor will be checking you regularly to monitor the effectiveness of the medication. Blood tests may be ordered for undesirable effects.
Check with your doctor if:
If you experience blurring of vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want your eyes checked by an ophthalmologist.
If you or your child have white patches in the throat, or pain when you eat or swallow. This medicine may cause thrush in the nose or throat.
If your or your child's symptoms did not improve within a few days or if they become worse.
If you or your child have bloody mucus, sores inside the nose, unexplained nosebleeds, or a whistling sound when you breathe while you are using this medicine. This medicine may increase your risk of having some unwanted effects in the nose.
If you or your child has any of the following symptoms: darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. This medicine may increase your risk of having an adrenal gland that is less active than normal. The adrenal gland makes steroids for your body. This is more likely for people who use steroids for a long time or use high doses.
This medicine may lower your body’s resistance temporarily. Avoid coming into close contact with sick people.
This medicine can cause dizziness or drowsiness. Avoid driving, operating machineries, or any other risky activities when you take this medication.
Your child's doctor will monitor your child’s height and weight since this medicine may cause slow growth in children.
This medicine will add to the effects of alcohol and other CNS depressants.
Check with your doctor before taking any of those medications while you are using morphine.
Talk to your doctor if you are taking any other medication.
5 Potential Side Effects
If any of the following side effects occur, check with your doctor as soon as possible.
Your FindaTopDoc account is completely free. Find doctors & request online appointments. Participate in Health Journeys in over 100 specialty communities. Easy & secure access! Simple Facebook login.
FindATopDoc is a trusted resource for patients to find the top doctors in their area. Be visible and accessible with your up to date contact
information, certified patients reviews and online appointment booking functionality.