Fareston is an oral selective estrogen receptor modulator used for the treatment of metastatic breast cancer in patients who have already stopped menstruating. This drug blocks the effects of the estrogen hormone in the body. Estrogen promotes the growth of breast tumors.
This drug requires a prescription.
2 What to Know Before Using
Before using Fareston, the risks and benefits for your body should be discussed with your healthcare provider.
Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.
Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.
This drug is contraindicated for use in the children. Safety and efficacy of this drug have not been established.
Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the utility of toremifene. Adjustments in the elderly may be required since they are more likely to have age-related liver problems.
Risks to fetuses have been reported in studies of pregnant women but these may be outweighed by the benefits of therapy in a life threatening situation or a serious disease.
Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about potential risks and benefits of taking this drug while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other drugs such as:
Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.
Inform your healthcare provider for any other medical problems such as:
To prevent any side effects, use Fareston exactly as directed in the label or as prescribed by your healthcare professional. This drug may cause mild nausea and vomiting. This drug may have to be taken for several weeks or months to be effective.
Consult with your healthcare professional before you stop using this drug. You can take this drug with or without food. The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.
The dosage of this drug you take depends on the medical problem for which you are using this drug.
A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.
Store the drug in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing. Keep out of the reach of children.
Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
In using Fareston, you must be careful and take some precautions as advised by your doctor.
Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness and unwanted effects of the drug. Unwanted effects can be screened by blood tests.
Women are recommended to have regular gynecologic check-ups while taking this drug. Postmenopausal women are unlikely to become pregnant. This drug has teratogenic potential and it is recommended to use an effective form of birth control to prevent any pregnancy from happening.
Inform your healthcare professional immediately if you think you have become pregnant while using the drug. This drug can cause QT prolongation which can manifest as fast, pounding, or uneven heartbeats.
Patients with bone problems are more likely to have hypercalcemia and tumor flare while taking this drug.
Check with your healthcare professional immediately if you have:
pain and swelling in the bones and muscles surrounding a tumor
thirst, unusual tiredness, or weight loss
This drug may cause Leukopenia which can increase your chance of getting an infection. It is recommended to avoid people with infections. Consult with your healthcare professional immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.
Touching your eyes or the inside of your nose without proper hand washing is not recommended. Be cautious in using sharp objects such as a safety razor or fingernail or toenail cutters to prevent any unnecessary wounds. It is recommended to avoid contact sports or other situations where bruising or injury could occur.
You may experience vaginal bleeding during the initial stages of therapy with this drug. The effects of Toremifene may be increased by taking grapefruits and grapefruit juice. You should not eat grapefruit or drink grapefruit juice while you taking this drug.
Consult with your healthcare professional before taking any other prescription or non-prescription drugs, and herbal or vitamin supplements.
5 Potential Side Effects
As with many medications, there are several potential side effects associated with Fareston.
Side effects may vary for each individual and prompt medical attention should be given if they occur. Some effects may have delayed onset for as long as months or years.
Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:
Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.
Report any side effects to the FDA hotline at 1-800-FDA-1088.
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