1 What is Tanzeum?

Brand: Tanzeum

Generic: Albiglutide

Tanzeum injection is used to treat type 2 diabetes mellitus. Tanzeum is used with diet and exercise to help control the blood sugar.

This medication is only available through your doctor’s prescription. This product is available in the following forms:

  • Powder for solution
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2 What to Know Before Using

Before using Tanzeum, you must know all about the risks and complications associated with it. This is a decision that you and your doctor will make together. 

For this medication, there are many things that need to be considered:

Allergies: Inform your doctor if you have ever had an allergic reaction to doxorubicin or to any other medications. It is also important to inform your doctor of any non-medicine allergies such as foods, dyes, preservatives or animals.

Pediatric : No appropriate studies have been performed on the relationship of age to the effects of this medication in children. Safety and efficacy have not been established.

Geriatric: Up-to-date studies have not shown any problems specific to the elderly that would limit the use of this medication in the elderly population.

Pregnancy: This medication is listed as Pregnancy Category C. This means that animal studies have shown an adverse effect and no studies have been performed on pregnant women OR there are no adequate studies on pregnant animals and pregnant women.

Breastfeeding: There are no up-to-date studies in women for determining infant risk when using this medication while breastfeeding. Weigh the potential risks with the benefits before taking this medication while breastfeeding.

Drug Interactions: Certain medications should not be used together. However, in certain cases, two medications may be used together, even if an interaction might occur. In these cases, your doctor may want to change your dose or take other precautions.

When taking this medication, it is important that you inform your doctor if you are taking any of the medications listed below. The following interactions were selected on the basis of potential significance and are not all-inclusive.

Using this medication with any of the following medication is not recommended, but may be unavoidable in some cases.

Your doctor may make the decision not to treat you with this medication or change some of the other medications you take:

  • Lanreotide
  • Octreotide
  • Pasireotide

Using this medication with any of the following medications may increase your risk of side effects. However, using both medications may be the best treatment for you.

If both medications are prescribed together, your doctor may change the dose or how often you take one or both medications:

  • Acebutolol
  • Atenolol
  • Betaxolol
  • Bisoprolol
  • Carteolol
  • Carvedilol
  • Celiprolol
  • Esmolol
  • Furazolidone
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Bovine
  • Insulin Degludec
  • Insulin Detemir
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Iproniazid
  • Isocarboxazid
  • Labetalol
  • Levobunolol
  • Linezolid
  • Methylene Blue
  • Metipranolol
  • Metoprolol
  • Moclobemide
  • Nadolol
  • Nebivolol
  • Nialamide
  • Oxprenolol
  • Penbutolol
  • Phenelzine
  • Pindolol
  • Practolol
  • Procarbazine
  • Propranolol
  • Rasagiline
  • Safinamide
  • Selegiline
  • Simvastatin
  • Sotalol
  • Timolol
  • Tranylcypromine

Other Interactions: Certain medications should not be used while eating, or while eating certain foods in case of negative interactions. Using alcohol or tobacco with certain medications may also cause negative interactions. Talk with your doctor about the use of your medication with food, alcohol or tobacco.

Other Medical Problems: Pre-existing medical problems may affect the use of this medication.

Be sure to tell your doctor if you have any other medical problems, especially:

  • Diabetic ketoacidosis (ketones in the blood)
  • Type 1 diabetes - Should not be used in patients with these conditions. Insulin is needed to control these conditions.
  • Gastroparesis, severe (delayed stomach emptying)
  • Multiple endocrine neoplasia syndrome types 2 (MEN 2)
  • Stomach or bowel disease (severe)
  • Medullary thyroid carcinoma (a type of thyroid cancer) - Should not be used in patients with these conditions.
  • Kidney disease
  • Thyroid tumor
  • Pancreatitis (inflammation of the pancreas) - It is not known if this medication will be safe with these patients.

3 Proper Usage

To use Tanzeum properly, you must follow all instructions given by your doctor. When you begin using this medication, it is very important to regularly monitor your blood sugar, especially before and after meals and before you go to bed. This will help lower the chance of having very low blood sugar (hypoglycemia).

This medication comes with a patient information brochure. It is very important that your read this information. Ask your doctor if you have any questions. You can take this medication with or without food.

You will use this medication at home. Your doctor will teach you how to administer the injections. Make sure you understand exactly how the medication is supposed to be injected.

This medication is given as a shot under the skin of your stomach, thighs or upper arm. Use a different body area each time you use this medication. Keep track of where you give each injection to make sure you rotate areas.

If you use this medication with insulin, do not mix them in the same syringe. You may inject this medication and insulin in the same body area, but they should not be administered right next to each other.

Be sure to allow the medication to warm to room temperature before injecting it. use it within 8 hours after it is mixed. If the medication in the pen has changed colour, looks cloudy or you see particles in it, do not use it. Do not shake the pen.

Use a new needle each time you inject your medication. This medication works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. It is best to use the doses on the same day each week.

Never share medication pens with others. It is not safe for one pen to be used for more than one person. Sharing needles or pens can result in transmission of infection.

Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Follow the special meal plan your doctor gave you. This is the most important part of controlling your condition and is necessary if the medication is to work properly. Exercise regularly and test for sugar in the blood or urine.

Dosing: Different patients will be given a different dose of this medication based on the strength of the medication. The number of doses you take each day, the time between doses and the length of time you take this medication depends on the reason you are taking this medication.

The following information only includes the average dose of this medication. If your dose is different, do not change it without first speaking to your doctor.

Adults: 30mg injected under the skin (subcutaneously) once a week. Your doctor may increase your dose to 50mg once a week as needed and until your blood sugar is controlled.

Children: Use and dose must be determined by your doctor.

Missed dose: If you miss a dose of this medication, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not double dose.

If you miss a dose, use it as soon as possible within 3 days after your missed dose. If you miss a dose by more than 3 days, wait until your next scheduled dose.

Storage: Store this medication in a closed container at room temperature. Keep it away from heat, moisture, and direct light. Do not freeze. Keep our of the reach of children

Do not keep expired medication or medication you no longer need. Ask your doctor how to dispose of any medication you do not use.

4 Precautions to Take

It is very important that your doctor checks in with you often while you are receiving Tanzeum to make sure that it is working properly. Blood and urine tests may be needed to check for unwanted effects.

It is very important that you follow any instructions from your health care team about:

Alcohol: Drinking alcohol may cause severe low blood sugar (hypoglycemia). Discuss this with your health care team.

Other medications: Do not take other medications during the time you use this medication unless you have asked your doctor. This includes over the counter medications such as aspirin and medications for appetite control, asthma, colds, cough, allergies or sinus problems.

Counselling: Other family members need to learn how to prevent or help with side effects. Diabetic patients may need special counselling about diabetes medication dosage changes that may occur because of lifestyle changes. Counselling on contraception and pregnancy may be needed because of the problems that may occur during pregnancy with this condition.

Travel: Keep a recent prescription and your medical history with you. Be prepared for an emergency. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times.

In the case of emergency: There may be a time when you need help for an emergency caused by your condition. It is a good idea to wear a medical identification bracelet or neck chain at all times. Carry an ID card in your wallet or purse that says you have diabetes and a list of all your medications.

Inform your doctor immediately if you experience the following while on this medication:

These may be signs of a serious thyroid problem. Pancreatitis may occur while using this medication.

Tell your doctor immediately if you have:

If you develop a skin rash, hives or any allergic reaction to this medication, stop taking the medication and inform your doctor.

This medication does not cause hypoglycemia. However, low blood sugar can occur when you use this medication with other medications that lower blood sugar, such as insulin, metformin or a sulfonylurea. Low blood sugar can also occur if you delay or miss a meal or snack, exercise more than usual, drink alcohol or cannot eat because of nausea and vomiting.

Symptoms of low blood sugar include:

  • anxiety
  • behaviour change similar to drunkenness
  • blurred vision
  • cold sweats
  • confusion
  • cool and pale skin
  • difficulty thinking or concentrating
  • drowsiness
  • excessive hunger
  • fast heartbeat (tachycardia)
  • a continuous headache
  • nausea
  • nervousness
  • nightmares
  • restless sleep
  • shakiness
  • slurred speech
  • unusual fatigue and weakness

If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey or sugar cubes or drink fruit juice, non-diet soft drink or sugar dissolved in water to relieve the symptoms. Check your blood for low blood sugar.

Glucagon is used in emergency situations where severe symptoms occur, such as convulsions or unconsciousness. Have a glucagon kit available, along with a syringe and needle, and know how to use it. Family members and friends should also know how to use it.

High blood sugar (hyperglycemia) may occur if you do not take enough doses or you skip a dose, overeat or do not follow your meal plan, have a fever or infection or do not exercise as much as normal.

Symptoms of hyperglycemia include:

  • blurred vision
  • dry mouth
  • flushed and dry skin
  • fruity breath odor
  • increased urination (polyuria)
  • ketones in the urine
  • loss of appetite
  • stomachache
  • nausea
  • vomiting
  • fatigue
  • difficulty breathing
  • unconsciousness
  • unusual thirst (polydipsia)

If symptoms of hyperglycemia occur, check your blood sugar levels and call your doctor for instructions.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Tanzeum. Although not all of these side-effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if you experience any of the following side-effects:


Some side effects that may occur do not normally need medical attention. These may leave as your body becomes accustomed to treatment. Ask your doctor about ways to prevent or reduce some of these side effects.

Talk to your doctor if any of the following side effects continue or are bothersome, or if you have questions:

More common:

  • Body aches or pain
  • Cough
  • Diarrhea
  • Ear congestion
  • Loss of voice
  • Muscle pain or stiffness
  • Pain in the joints
  • Pain or tenderness around the eyes and cheekbones
  • Skin reactions, warmth, or redness at the injection site
  • Sneezing
  • Stuffy or a runny nose

Some patients may experience other side effects that are not listed. Check with your doctor if you notice any other side effects. Ask your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.