Yes, you can help your wife, which will be helpful to you and your newborn as well. Post-partum depression, as you know, is not uncommon, and should not persist with good treatment. Find out if your wife's therapist is agreeable to you coming to sessions with her. This is a family matter, and discussing your concerns for your wife, for yourself, and for your newborn (if your wife is unable to bond with him, which is sometimes the case), openly and non-judgmentally, would be helpful. If your wife's therapist is not open to this--or doesn't have experience with couples' or family treatment, ask for a referral. It would be helpful for you to ask both your wife and her therapist how you can help. Taking action this way will go a long way towards letting your wife know that you are in this together. Also, if she is seeing a nonmedical practitioner, she should be evaluated for medication by a psycho-pharmacologist to help her recover from this common episode. It should not be needed after she has recovered, but the appropriateness should be explored. Many family members hold back from candid communication with their loved ones for fear they will say the wrong thing and make things worse. The partner then may interpret this as not caring or rejections. Don't be afraid to talk to your wife. But plan out what you will say, you want to nonjudgmentally express your concerns and ask her how you can help. She may be too depressed to answer, but she will take in your caring overture. Make sure you are in a calm frame of mind before discussing. You can always role play what you would say with a friend. Finally, if you are concerned that your child may be negatively impacted, do not hesitate to see your paediatrician, or get additional help in the household in the short-run, while she is recovering.