1 What is Cylert?

Brand: Cylert

Generic: Pemoline

Brand name:


Pemoline is a central nervous system stimulant that is indicated for children with attention-deficit hyperactivity disorder or ADHD.

It works by increasing children’s ability to focus and concentrate while decreasing their restlessness. Pemoline is used together with the educational, social, and psychological treatment of ADHD.

This allows a more holistic approach. You also need to be aware that this medication is known to cause serious liver damage.

Your doctor will ask you to sign an Informed Consent Form before proceeding with treatment.

Pemoline can only be purchased with a physician’s prescription. It is usually sold as regular tablets and chewable tablets.

2 What to Know Before Using

As mentioned earlier, you will be asked to sign an Informed Consent Form before the treatment is started. In order to do this, however, you need to be aware of all the risks and benefits associated with pemoline use.

This medication should not be given to patients who have had hypersensitivity reactions to it or to similar medications. You also need to inform your doctor if you have any food, dye, preservative, or animal allergies.

This medication may hamper your child’s normal development if it is used for a long time. Your physician may prescribe medicine-free periods in order to prevent this.

Not enough research has been conducted regarding the effects of pemoline on patients age 65 and older. However, it is recommended that the pemoline dosing in geriatric patients should be done with caution since they are more at risk of developing hepatic, renal, or cardiac problems.

Pemoline should be used in pregnant women only when the benefits outweigh the risks because there isn’t enough research regarding its effects on the unborn child. The same goes for nursing mothers.

Patient receiving pemoline and other CNS-acting drugs should be monitored carefully.

Inform your healthcare provider if you have the following:

Pemoline can make these conditions worse.

3 Proper Usage

Follow the instructions given by your physician regarding pemoline dosage, timing, and frequency. Also, adhere to the duration of treatment prescribed by your doctor.

Chewable tablets should not be swallowed whole. It should be chewed first. The therapeutic effects of pemoline may take up to 4 weeks to manifest.

The dosage and timing of this medication are different for each individual. It depends on the severity of your condition and strength of the medication.

Generally, though, children are told to take 37.5 mg once daily every morning. Your doctor may increase it gradually to not more than 112.5 mg daily.

For children 6 years old and younger, the dosage is yet to be determined by the doctor. If you or your child missed a dosing, take it as soon as possible.

Do not take it if it is almost time to take the next one. Keep your pemoline tablets in a sealed container at room temperature. Make sure children cannot reach it.

4 Precautions to Take

Go to your follow-up appointments diligently. If you miss one, reschedule it as soon as possible. Your doctor needs to monitor your or your child’s condition to ensure that pemoline is working well.

This is also a way for your healthcare provider to check for unwanted effects and treat them right away. Blood exams will also be necessary for making sure the liver is not affected negatively by pemoline.

There are several symptoms you need to watch out for while you are taking this medication. Consult your physician immediately if you start having yellow skin or eyes.

These suggest serious liver involvement. Pemoline can also cause dizziness, so do not drive or let your child engage in strenuous activities like riding a bike. This medication can also cause dependence.

Some signs of substance dependence include a strong desire to continue taking the medicine and increase the dose to receive the desirable effects of the medicine.

Another way to tell if there is dependence is to watch out for withdrawal side effects after the medicine is stopped. If you or child experiences these, consult your healthcare provider right away.

Do not stop taking this medication abruptly. Check with your doctor first as he/she may taper it down before completely stopping it.

5 Potential Side Effects

Pemoline may also cause side effects other than those mentioned earlier. However, you may not experience all of these at the same time.

Get medical attention immediately if you or your child exhibits signs of overdose, which include the following:

  • confusion
  • agitation
  • seizures
  • fast heartbeat
  • hallucinations
  • headache
  • hypertension
  • high fever
  • large pupils
  • muscle twitching
  • restlessness
  • sweating and vomiting

Again, you need to watch out for signs of liver damage including dark urine and yellow discoloration of skin and eyes.

Rare side effects shortness of breath, troubled breathing, wheezing, skin rashes, mouth or lip sores, painful glands, unusual bleeding or bruising, unusual tiredness, and uncontrolled movements of eyes, tongue, lips, face, arms, or legs.

Again, not all of these will manifest. If you do experience side effects that are not listed here or if they persist, consult your physician right away.

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